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RP-1246 — Optimization of Cryosurgical Probes for Cancer Treatment

Original price was: $30.00.Current price is: $15.00.

Report / Survey by ASHRAE, 2005

Category:

Description

A commercial equation solving program is used to model the thermodynamic cycle of a commercially available cryosurgical probe and to model the resulting iceball growth. These models, together with the refrigerant mixture optimization method of Keppler et al. (2004) are combined to form a design method in which the iceball size produced by a cryoprobe with a given set of mixture constituents is maximized by altering the concentrations of each constituent. Experimental work to validate the iceball model for pure argon as a refrigerant displays good agreement over a range of operating pressures (1323-3000 psi), while experimental work to validate the thermodynamic cycle model of the cryoprobe shows good agreement at low pressures (1323 psig), and less favorable agreement at higher pressures (3000 psig). Design charts are generated so that the cryoprobe design method developed for a single heat exchanger geometry may be applied to any cryoprobe with a known heat exchanger conductance and known active area.


Principal Investigator: Kylie L. Fredrickson, Gregory F. Nellis,Sanford A. Klein

Conducted: June 2005

Sponsored by: TC 10.4,Ultra-Low Temperature Refrigeration & Cryogenics

Product Details

Published:
2005
File Size:
1 file , 3.1 MB
Product Code(s):
D-27205